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PubMed ID:
29111115
Public Release Type:
Journal
Publication Year: 2018
Affiliation: Temple University, Philadelphia, PA.
DOI:
https://doi.org/10.1053/j.gastro.2017.08.033
Authors:
Hamilton FA,
Parkman HP,
NIDDK Gastroparesis Clinical Research Consortium (GpCRC),
Snape WJ,
DeVole N,
Earle K,
Kirkeby K,
Lee C,
Lin M,
Ponting K,
Yee G,
Pasricha PJ,
Clarke JO,
Stein E,
Dhalla S,
Kim Y,
Nguyen LAB,
Garay G,
Orlando C,
Parkman HP,
Mauer A,
Orthey P,
Palit A,
McCallum RW,
Sarosiek I,
Connery S,
Gomez Y,
Romero R,
Vega N,
Alvarado B,
Abell TL,
Hatter L,
Howard R,
Nowotny L,
Hasler WL,
Herman W,
Kraftson A,
Rothberg AE,
Wootten S,
Koch KL,
Baxter L,
Brown A,
Stuart P,
Farrugia G,
Grover M,
Bernard C,
Hamilton F,
Serrano J,
James S,
Torrance R,
Hall S,
Tonascia J,
Belt P,
Dodge J,
Donithan M,
Hallinan E,
Isaacson M,
Lee LA,
May PK,
Miriel L,
Sternberg A,
Van Natta M,
Wagoner A,
Wilson L,
Yates KP,
Culler S,
Pasricha PJ,
Yates KP,
Sarosiek I,
McCallum RW,
Abell TL,
Koch KL,
Nguyen LAB,
Snape WJ,
Hasler WL,
Clarke JO,
Dhalla S,
Stein EM,
Lee LA,
Miriel LA,
Van Natta ML,
Grover M,
Farrugia G,
Tonascia J
Studies:
Aprepitant for the Relief of Nausea in Patients With Chronic Nausea and Vomiting of Presumed Gastric Origin Trial
There are few effective treatments for nausea and other symptoms in patients with gastroparesis and related syndromes. We performed a randomized trial of the ability of the neurokinin-1 receptor antagonist aprepitant to reduce symptoms in patients with chronic nausea and vomiting caused by gastroparesis or gastroparesis-like syndrome.
