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PubMed ID:
25921377
Public Release Type:
Journal
Publication Year: 2015
Affiliation: Biomedical Statistics and Informatics, Mayo Clinic, Rochester, Minnesota.
DOI:
https://doi.org/10.1053/j.gastro.2015.04.020
Authors:
Zinsmeister AR,
Tilkes KE,
Schleck CD,
Hamilton FA,
Camilleri M,
Szarka LA,
Herrick LM,
Moayyedi P,
El-Serag HB,
Lacy BE,
DiBaise JK,
Prather CM,
Abraham BP,
Talley NJ,
Locke GR,
Saito YA,
Almazar AE,
Bouras EP,
Howden CW
Studies:
Functional Dyspepsia Treatment Trial
Antidepressants are frequently prescribed to treat functional dyspepsia (FD), a common disorder characterized by upper abdominal symptoms, including discomfort or postprandial fullness. However, there is little evidence of the efficacy of these drugs in patients with FD. We performed a randomized, double-blind, placebo-controlled trial to evaluate the effects of antidepressant therapy on symptoms, gastric emptying (GE), and meal-induced satiety in patients with FD.
