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Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial.

Parkman HP, Van Natta ML, Abell TL, McCallum RW, Sarosiek I, Nguyen L, Snape WJ, Koch KL, Hasler WL, Farrugia G, Lee L, Unalp-Arida A, Tonascia J, Hamilton F, Pasricha PJ. Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial. JAMA 2013 Dec 25;310(24):2640-9.

PubMed ID: 24368464
Public Release Type: Journal
Publication Year: 2013
Affiliation: The Johns Hopkins Hospital, Baltimore, Maryland.
DOI: https://doi.org/10.1001/jama.2013.282833
Authors: Hasler WL, Koch KL, Snape WJ, Nguyen L, Sarosiek I, McCallum RW, Abell TL, Van Natta ML, Parkman HP, Pasricha PJ, Hamilton F, Tonascia J, Unalp-Arida A, Lee L, Farrugia G
Studies: Gastroparesis Clinical Research Consortium , Nortriptyline for Idiopathic Gastroparesis

Abstract

Gastroparesis remains a challenging syndrome to manage, with few effective treatments and a lack of rigorously controlled trials. Tricyclic antidepressants are often used to treat refractory symptoms of nausea, vomiting, and abdominal pain. Evidence from well-designed studies for this use is lacking.

Home chevron_right Publications chevron_right Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial.

Effect of nortriptyline on symptoms of idiopathic gastroparesis: the NORIG randomized clinical trial.

Abstract