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Public Release Type:
Journal
Publication Year: 2013
Authors:
Tonascia J,
Chalasani NP,
Tetri BA,
Masuoka HC,
Comerford M,
Yates KP,
Deppe RB,
Vuppalanchi R,
Loomba R,
Brunt E,
Kleiner DE
Studies:
Nonalcoholic Steatohepatitis Clinical Research Network
,
The Nonalcoholic Steatohepatitis Research Network (NASH CRN) Pioglitazone vs Vitamin E vs Placebo for Treatment of Non-Diabetic Patients With Nonalcoholic Steatohepatitis
Previous cross-sectional studies have shown that serum levels of cytokeratin fragments (CK18) are associated with the presence of steatohepatitis in individuals with nonalcoholic fatty liver disease (NAFLD). However, it is unknown if serial serum CK18 levels can predict longitudinal changes in liver histology in NAFLD.
