PubMed ID:
22153382
Public Release Type:
Journal
Publication Year: 2012
Affiliation: Nutrition and Neurocognition Laboratory, Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts, USA. troen@agri.huji.ac.il
DOI:
https://doi.org/10.1053/j.jrn.2011.07.009
Authors:
Sundberg AK,
Sanmugalingham G,
Ford H,
Famure S,
Blackmore J,
Cole E,
McKenney J,
Bostom A,
Medeiros M,
McDaniel B,
Osborne J,
LaBeck T,
Norman D,
Parks R,
Kendrach A,
Jones P,
Kew CE 2nd,
Armbruster B,
Coffman J,
Mace N,
Smith SR,
Wallace W,
Diltz C,
Lowe T,
Hunsicker L,
Bullas R,
Edgar MJ,
McRae E,
House A,
Pagels J,
Clark R,
Gaynor S,
Lyman PR,
Anderson-Haag T,
Bresnahan B,
Kasiske B,
FACT Study Investigators,
Rosenberg IH,
Selhub J,
Jacques PF,
Dallal GE,
Levey AS,
Weiner DE,
Rogers G,
Dobson B,
Moorthy D,
D'Anci KE,
Scott TM,
Troen AM,
Pence D,
Kumar A,
Edwards C,
Gifford-Hollingsworth C,
Bolin P Jr,
Parker K,
Garris C,
Bryant W,
Carpenter MA,
Pacheco-Silva A,
Bolognani S,
Riley J,
Okano I,
Quintino P,
Giordan M,
Mahler K,
McDaniel B,
Pesavento T,
Radke N,
Groth J,
Pirsch J,
Miedwig L,
Alfrey EJ,
Garrison K,
Vella J,
Gnadt C,
Hertello P,
Farag YM,
Singh A,
Berndt M,
Cosio F,
Lion M,
Seliger S,
Young C,
Anandagoda Lde S,
Weir M,
Vermillion M
Studies:
Folic Acid for Vascular Outcome Reduction in Transplantation Trial
Hyperhomocysteinemia and B-vitamin deficiency may be treatable risk factors for cognitive impairment and decline. Hyperhomocysteinemia, cognitive impairment, and depression are all common in individuals with kidney disease, including kidney transplant recipients. Accordingly, we assessed the prevalence of cognitive impairment and depressive symptoms in transplant recipients and their association with kidney function, plasma total homocysteine, and B-vitamin concentrations.