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PubMed ID:
21454968
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Genetic Analysis and Data Coordinating Center, Cleveland, Ohio, USA.
DOI:
https://doi.org/10.1159/000326763
Authors:
Rasooly RS,
Igo RP Jr,
Iyengar SK,
Nicholas SB,
Goddard KA,
Langefeld CD,
Hanson RL,
Duggirala R,
Divers J,
Abboud H,
Adler SG,
Arar NH,
Horvath A,
Elston RC,
Bowden DW,
Guo X,
Ipp E,
Kao WH,
Kimmel PL,
Knowler WC,
Meoni LA,
Molineros J,
Nelson RG,
Pahl MV,
Parekh RS,
Schelling JR,
Shah VO,
Smith MW,
Winkler CA,
Zager PG,
Sedor JR,
Freedman BI,
Family Investigation of Nephropathy and Diabetes Research Group
Studies:
Family Investigation of Nephropathy and Diabetes
Diabetic nephropathy (DN) is a leading cause of mortality and morbidity in patients with type 1 and type 2 diabetes. The multicenter FIND consortium aims to identify genes for DN and its associated quantitative traits, e.g. the urine albumin:creatinine ratio (ACR). Herein, the results of whole-genome linkage analysis and a sparse association scan for ACR and a dichotomous DN phenotype are reported in diabetic individuals.
