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PubMed ID:
21036173
Public Release Type:
Journal
Publication Year: 2011
Affiliation: Department of Pediatrics, Division of Gastroenterology and Nutrition, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. kschwarz@jhmi.edu
DOI:
https://doi.org/10.1053/j.gastro.2010.10.047
Authors:
Haber BA,
Rossi S,
Lobritto SJ,
Smith L,
Narkewicz MR,
Balistreri WF,
Robuck PR,
Goodman Z,
Valsamakis A,
Peds-C Clinical Research Network,
Mohan P,
Rosenthal P,
Jonas MM,
Barton BA,
Molleston JP,
Murray KF,
Gonzalez-Peralta RP,
Schwarz KB
Studies:
Pegylated Interferon +/- Ribavirin for Children with HCV
Although randomized trials of adults infected with hepatitis C virus (HCV) have shown that ribavirin increases the efficacy of pegylated interferon (PEG), such trials have not been performed in children. We conducted a randomized controlled trial of PEG and ribavirin, compared with PEG and placebo, in children 5 to 17 years old with chronic hepatitis C.
