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PubMed ID:
15606694
Public Release Type:
Journal
Publication Year: 2005
Affiliation: Division of Medical Sciences, University of Birmingham, Birmingham Heartlands Hospital, UK. ashpat100@hotmail.com
DOI:
https://doi.org/10.1111/j.1464-5491.2005.01376.x
Authors:
Barnett AH,
Warren 3/UK GoKind Study Group,
Bain SC,
Scott WR,
Patel A,
Lympany PA,
Rippin JD,
Gill GV
Studies:
The Genetics of Kidneys in Diabetes
We hypothesize that transforming growth factor-beta (TGF-beta), a multifunctional growth factor which plays a key role in the development of tissue fibrosis, may be involved in the pathophysiology of diabetic nephropathy. Our aim was to examine three polymorphisms within the TGF-beta 1 gene, in codons 10, 25 and 263, for association with nephropathy in Type 1 diabetes.
