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PubMed ID:
12911554
Public Release Type:
Journal
Publication Year: 2003
Affiliation: Department of Medicine (Renal Division), University of Alabama at Birmingham, Birmingham, Alabama, USA. arlene_chapman@emory.org
DOI:
https://doi.org/10.1046/j.1523-1755.2003.00185.x
Authors:
Baumgarten DA,
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease cohort,
Miller JP,
Thompson PA,
Kimmel PL,
Hirschman GH,
Klahr S,
Bennett WM,
Robbin ML,
O'Neill WC,
Brummer ME,
Wetzel LH,
Glockner JF,
King BF Jr,
Kenney PJ,
Bae KT,
Torres VE,
Grantham JJ,
Guay-Woodford LM,
Chapman AB
Studies:
Consortium for Radiologic Imaging Studies of Polycystic Kidney Disease
Autosomal-dominant polycystic kidney disease (ADPKD) is characterized by gradual renal enlargement and cyst growth prior to loss of renal function. Standard radiographic imaging has not provided the resolution and accuracy necessary to detect small changes in renal volume or to reliably measure renal cyst volumes. The Consortium for Radiologic Imaging Studies in Polycystic Kidney Disease (CRISP) is longitudinally observing ADPKD individuals using high-resolution magnetic resonance (MR) imaging to determine if change in renal and cyst volumes can be detected over a short period of time, and if they correlate with decline in renal function early in disease.
