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PubMed ID:
36219773
Public Release Type:
Journal
Publication Year: 2022
Affiliation: Section of Nephrology, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Renal Section, Evans Biomedical Research Center, 650 Albany Street, X504, Boston, MA 02118, USA.; Center for Adrenal Disorders, Division of Endocrinology, Diabetes, and Hypertension, Brigham and women's Hospital, Boston, MA 02115, USA.; Department of Radiation Oncology, Massachusetts General Hospital, Boston, MA 02114, USA.; Section of Nephrology, Department of Medicine, Boston University School of Medicine and Boston Medical Center, Renal Section, Evans Biomedical Research Center, 650 Albany Street, X504, Boston, MA 02118, USA.
DOI:
https://doi.org/10.1093/eurheartj/ehac352
Authors:
Verma Ashish, Vaidya Anand, Subudhi Sonu, Waikar Sushrut S
Request IDs:
22526
Studies:
Chronic Renal Insufficiency Cohort Study
Randomized controlled trials have demonstrated the efficacy of mineralocorticoid receptor (MR) antagonism in delaying chronic kidney disease (CKD) progression in diabetes; however, they have not investigated the role of aldosterone or whether these beneficial effects could be achieved in individuals without diabetes.
