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PubMed ID:
33538814
Public Release Type:
Journal
Publication Year: 2021
Affiliation: Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Clinical Research Center, Maoming People's Hospital, Guangdong, China.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.; Montreal Children's Hospital and the Endocrine Genetics Laboratory, Child Health and Human Development Program, the Research Institute of the McGill University Health Centre, Montreal, Canada.
DOI:
https://doi.org/10.1210/clinem/dgab056
Authors:
Marchand Luc, Li Meihang, Leblicq Coralie, Rafique Ibrar, Alarcon-Martinez Tugba, Lange Claire, Rendon Laura, Tam Emily, Courville-Le Bouyonnec Ariane, Polychronakos Constantin
Request IDs:
21185
Studies:
Type 1 Diabetes Genetics Consortium
About 1% of patients clinically diagnosed as type 1 diabetes have non-autoimmune monogenic diabetes. The distinction has important therapeutic implications but, given the low prevalence and high cost of testing, selecting patients to test is important. We tested the hypothesis that low genetic risk for type 1 diabetes can substantially contribute to this selection.
