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PubMed ID:
32894582
Public Release Type:
Journal
Publication Year: 2021
DOI:
https://doi.org/10.1111/jgs.16797
Authors:
Chen Teresa K., Coresh Josef, Daya Natalie, Ballew Shoshana H., Tin Adrienne, Crews Deidra C., Grams Morgan E.
Request IDs:
20733
,
21008
,
21579
Studies:
African American Study of Kidney Disease and Hypertension Study (Clinical Trial)
APOL1 high-risk genotypes confer an increased risk for kidney disease, but their clinical significance among older adults remains unclear. We aimed to determine whether APOL1 genotype status (high risk = 2 risk alleles; low risk = 0–1 risk alleles) and self-reported race (Black; White) are associated with number of hospitalizations, incident chronic kidney disease (CKD), end-stage renal disease (ESRD), and mortality among older adults participating in a community-based cohort study.
