PubMed ID:
27688741
Public Release Type:
Journal
Publication Year: 2016
Affiliation: Department of Oncology, Georgetown University, PS Room GD11, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Building D Suite 180 Room 185, 4000 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Biostatistics, Bioinformatics, and Biomathematics, Georgetown University, Basic Science Building D Room 255, 3900 Reservoir Rd NW, Washington, DC 20057 USA.; MedStar Georgetown University Transplant Institute, 2-PHC, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA USA.; Department of Oncology, Georgetown University, PS Room GD11, 3800 Reservoir Rd NW, Washington, DC 20057 USA.; Department of Oncology, Georgetown University, NRB Room E207, 3970 Reservoir Rd NW, Washington, DC 20057 USA.
DOI:
https://doi.org/10.1186/s12014-016-9125-x
Authors:
Sanda Miloslav, Benicky Julius, Wu Jing, Wang Yiwen, Makambi Kepher, Ahn Jaeil, Smith Coleman I, Zhao Peng, Zhang Lihua, Goldman Radoslav
Request IDs:
20623
Studies:
The Hepatitis C Antiviral Long-Term Treatment Against Cirrhosis Trial
Non-invasive monitoring of liver disease remains an important health issue. Liver secreted glycoproteins reflect pathophysiological states of the organ and represent a rational target for serologic monitoring. In this study, we describe sialylated O-glycoforms of liver-secreted hemopexin (HPX) and quantify them as a ratio of disialylated to monosialylated form (S-HPX).