Official websites use .gov
A
.gov
website belongs to an official government organization in the
United States.
Secure .gov websites use HTTPS
A
lock
(
) or
https://
means you’ve safely connected to the .gov website. Share sensitive
information only on official, secure websites.
PubMed ID:
26278503
Public Release Type:
Journal
Publication Year: 2015
DOI:
https://doi.org/10.1053/j.gastro.2015.07.065
Authors:
Huang Chengrui, Haritunians Talin, Okou David T., Cutler David J., Zwick Michael E., Taylor Kent D., Datta Lisa W., Maranville Joseph C., Liu Zhenqiu, Ellis Shannon, Chopra Pankaj, Alexander Jonathan S., Baldassano Robert N., Cross Raymond K., Dassopoulos Themistocles, Dhere Tanvi A., Duerr Richard H., Hanson John S., Hou Jason K., Hussain Sunny Z., Isaacs Kim L., Kachelries Kelly E, Kader Howard, Kappelman Michael D., Katz Jeffrey, Kellermayer Richard, Kirschner Barbara S., Kuemmerle John F., Kumar Archana, Kwon John H., Lazarev Mark, Mannon Peter, Moulton Dedrick E., Osuntokun Bankole O., Patel Ashish, Rioux John D., Rotter Jerome I., Saeed Shehzad, Scherl Ellen J., Silverberg Mark S., Silverman Ann, Targan Stephan R., Valentine John F., Wang Ming-Hsi, Simpson Claire L., Bridges S. Louis, Kimberly Robert P., Rich Stephen S., Cho Judy H., Rienzo Anna Di, Kao Linda W.H., McGovern Dermot P.B., Brant Steven R., Kugathasan Subra
Request IDs:
20778
Studies:
Inflammatory Bowel Disease Genetics
Inflammatory bowel disease (IBD) has familial aggregation in African Americans (AAs), but little is known about the molecular genetic susceptibility. Mapping studies using the Immunochip genotyping array expand the number of susceptibility loci for IBD in Caucasians to 163, but the contribution of the 163 loci and European admixture to IBD risk in AAs is unclear. We performed a genetic mapping study using the Immunochip to determine whether IBD susceptibility loci in Caucasians also affect risk in AAs and identify new associated loci.
