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Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection.

PubMed ID: 30743006
Public Release Type: Journal
Publication Year: 2019
Affiliation: Division of Gastroenterology, Toronto General Hospital, University Health Network, Toronto, Canada.; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Division of Gastroenterology, Toronto General Hospital, University Health Network, Toronto, Canada; IHPME, University of Toronto, Toronto, Canada.; Division of Gastroenterology, University of California-San Francisco, San Francisco, California.; Division of Gastroenterology and Hepatology, University of Michigan, Ann Arbor, Michigan.; Division of Gastroenterology, Baylor University Medical Center, Dallas, Texas.; Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Division of Gastroenterology and Hepatology, Saint Louis University, St Louis, Missouri.; Division of Gastroenterology, Toronto General Hospital, University Health Network, Toronto, Canada.; Division of Digestive and Liver Diseases, University of Texas Southwestern Medical Center, Dallas, Texas.; Division of Gastroenterology and Hepatology, University of North Carolina, Chapel Hill, North Carolina.; Division of Gastroenterology, Toronto General Hospital, University Health Network, Toronto, Canada. Electronic address: Harry.Janssen@uhn.ca.
DOI: https://doi.org/10.1016/j.cgh.2019.02.005
Authors: Brahmania Mayur, Lombardero Manuel, Hansen Bettina E, Terrault Norah A, Lok Anna S, Perrillo Robert P, Belle Steven H, Di Bisceglie Adrian M, Feld Jordan J, Lee William M, Fried Michael W, Janssen Harry L A
Request IDs: 20876 , 21197
Studies: Hepatitis B Research Network Adult Cohort Study

Abstract

The incidence and outcomes of alanine aminotransferase (ALT) flares during the natural history of chronic HBV infection has not been determined in a large, racially heterogeneous group of patients in North America.

Home chevron_right Publications chevron_right Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection.

Association Between Severe Serum Alanine Aminotransferase Flares and Hepatitis B e Antigen Seroconversion and HBV DNA Decrease in Untreated Patients With Chronic HBV Infection.

Abstract