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PubMed ID:
30228110
Public Release Type:
Journal
Publication Year: 2018
DOI:
https://doi.org/10.2215/CJN.05850518
Authors:
Nowak Kristen L., Wang Wei, Farmer-Bailey Heather, Gitomer Berenice, Malaczewski Mikaela, Klawitter Jelena, Jovanovich Anna, Chonchol Michel
Request IDs:
20959
Studies:
The HALT Progression of Polycystic Kidney Disease (HALT-PKD)
Both increased arterial stiffness and vascular endothelial dysfunction are evident in patients with autosomal dominant polycystic kidney disease, even early in the course of the disease when kidney function in preserved. Vascular dysfunction in autosomal dominant polycystic kidney disease is thought to be related to vascular oxidative stress and inflammation, but direct evidence is lacking.
