Official websites use .gov
A
.gov
website belongs to an official government organization in the
United States.
Secure .gov websites use HTTPS
A
lock
(
) or
https://
means you’ve safely connected to the .gov website. Share sensitive
information only on official, secure websites.
PubMed ID:
35777833
Public Release Type:
Journal
Publication Year: 2022
Affiliation: Boston University School of Medicine, Boston, Massachusetts.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.; Department of Genetic Medicine, McKusick-Nathans Institute, Johns Hopkins University, Baltimore, Maryland.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.; Welch Center for Prevention, Epidemiology, and Clinical Research, Johns Hopkins University, Baltimore, Maryland.
DOI:
https://doi.org/10.2215/CJN.15551121
Authors:
He William J, Li Changwei, Huang Zhijie, Geng Siyi, Rao Varun S, Kelly Tanika N, Hamm L Lee, Grams Morgan E, Arking Dan E, Appel Lawrence J, Rebholz Casey M
Request IDs:
21020
Studies:
Chronic Renal Insufficiency Cohort Study
Mitochondrial DNA copy number is a biomarker of mitochondrial function, which has been hypothesized to contribute to pathogenesis of CKD through podocyte injury, tubular epithelial cell damage, and endothelial dysfunction. The prospective association of mitochondrial DNA copy number with CKD progression has not been previously evaluated.
