PubMed ID:
32729368
Public Release Type:
Journal
Publication Year: 2020
DOI:
https://doi.org/10.1080/14728214.2020.1803276
Authors:
Trachtman Howard
Request IDs:
21203
Studies:
FONT 2 Study: Novel Therapies for Resistant FSGS Phase II Clinical Trials
Glomerulosclerosis represents the final stage of glomerular injury during the course of kidney disease and can represent a primary disturbance in disorders like focal segmental glomerulosclerosis or a secondary response to tubulointerstitial disease. Overall, primary focal glomerulosclerosis (FSGS), the focus of this review, accounts for 10–20% of patients of all ages who progress to end stage kidney disease. There are no FDA approved therapeutic options that effectively prevent or delay the onset of kidney failure.