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PubMed ID:
29470286
Public Release Type:
Journal
Publication Year: 2018
Affiliation: Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University, New York, NY.; Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University, New York, NY.; Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University, Indianapolis, IN.; Institute for Translational Genomics and Population Science and Pediatrics, LA BioMed at Harbor-UCLA Medical Center, Los Angeles.; Institute for Translational Genomics and Population Science and Pediatrics, LA BioMed at Harbor-UCLA Medical Center, Los Angeles.; Division of Gastroenterology, Hepatology and Nutrition in the Department of Pediatrics, University of California, San Diego, San Diego, CA.; Division of Gastroenterology, Hepatology and Nutrition.; Division of Gastroenterology and Hepatology, Department of Medicine, University of California, San Diego, San Diego, CA.; Departments of Pathology and Immunology, Washington University, St. Louis, MO.; Institute for Translational Genomics and Population Science and Pediatrics, LA BioMed at Harbor-UCLA Medical Center, Los Angeles.; Division of Endocrinology, Diabetes and Metabolism, Cedars-Sinai Medical Center, Los Angeles, CA.; Institute for Translational Genomics and Population Science and Pediatrics, LA BioMed at Harbor-UCLA Medical Center, Los Angeles.; Department of Pediatrics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD.; Institute for Translational Genomics and Population Science and Pediatrics, LA BioMed at Harbor-UCLA Medical Center, Los Angeles.
DOI:
https://doi.org/10.1097/MPG.0000000000001926
Authors:
Rausch John C, Lavine Joel E, Chalasani Naga, Guo Xiuqing, Kwon Soonil, Schwimmer Jeffrey B., Molleston Jean P, Loomba Rohit, Brunt Elizabeth M, da Chen Yii-Der I, Goodarzi Mark O, Taylor Kent D, Yates Katherine P, Rotter Jerome I
Request IDs:
21293
Studies:
Genetics of Pediatric Nonalcoholic Fatty Liver Disease
Nonalcoholic fatty liver disease (NAFLD) disproportionately affects Hispanic boys. Further, obesity and insulin resistance are major risk factors for NAFLD. No gene localization studies had been performed on children with biopsy-proven NAFLD. This study aims to identify genomic variants associated with increased adiposity and insulin resistance in a population of children with varying histologic severity of NAFLD.
