Official websites use .gov
A
.gov
website belongs to an official government organization in the
United States.
Secure .gov websites use HTTPS
A
lock
(
) or
https://
means you’ve safely connected to the .gov website. Share sensitive
information only on official, secure websites.
PubMed ID:
32580032
Public Release Type:
Journal
Publication Year: 2020
DOI:
https://doi.org/10.1016/j.cct.2020.106067
Authors:
Rodríguez Luis A., Barquera Simón, Aguilar-Salinas Carlos A., Sepúlveda-Amor Jaime, Sánchez-Romero Luz María, Denova-Gutiérrez Edgar, Balderas Nydia, Moreno-Loaeza Lizbeth, Handley Margaret A., Basu Sanjay, López-Arellano Oliva, Gallardo-Hernóndez Alberto, Schillinger Dean
Request IDs:
21387
Studies:
Diabetes Prevention Program
Type 2 diabetes (T2D) is a global epidemic, and nations are struggling to implement effective healthcare strategies to reduce the burden. While efficacy studies demonstrate that metformin can reduce incident T2D by half among younger, obese adults with prediabetes, its real-world effectiveness are understudied, and its use for T2D prevention in primary care is low. We describe the design of a pragmatic trial to evaluate the incremental effectiveness of metformin, as an adjunct to a simple lifestyle counseling.
