PubMed ID:
35072049
Public Release Type:
Journal
Publication Year: 2022
Affiliation: Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Center for Translational Metabolism and Health, Institute for Public Health and Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora.; Division of Nephrology and Hypertension, Department of Medicine, Tulane University School of Medicine, New Orleans, Louisiana.; Division of Cardiology, Electrophysiology Section, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.; Division of Nephrology, Department of Medicine, University of Illinois, Chicago.; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana.; Comprehensive Clinical Research Unit, Kaiser Permanente Northern California Division of Research, Oakland, California.; Renal Electrolyte and Hypertension Division, Department of Medicine, Department of Biostatistics, Epidemiology, and Informatics, and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.; Division of Nephrology, Department of Medicine, University of Mississippi Medical Center, Jackson.; Division of Nephrology, Department of Medicine, Massachusetts General Hospital, Boston.; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora.; Division of Renal Diseases and Hypertension, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora.; Division of Nephrology and Hypertension, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
DOI:
https://doi.org/10.1016/j.xkme.2021.09.004
Authors:
Frazier Rebecca, Cai Xuan, Lee Jungwha, Bundy Joshua D, Jovanovich Anna, Chen Jing, Deo Rajat, Lash James P, Anderson Amanda Hyre, Go Alan S, Feldman Harold I, Shafi Tariq, Rhee Eugene P, Miyazaki Makoto, Chonchol Michel, Isakova Tamara
Request IDs:
21734
,
23163
Studies:
Chronic Renal Insufficiency Cohort Study
Elevated levels of deoxycholic acid (DCA) are associated with adverse outcomes and may contribute to vascular calcification in patients with chronic kidney disease (CKD). We tested the hypothesis that elevated levels of DCA were associated with increased risks of cardiovascular disease, CKD progression, and death in patients with CKD.