Official websites use .gov
A
.gov
website belongs to an official government organization in the
United States.
Secure .gov websites use HTTPS
A
lock
(
) or
https://
means you’ve safely connected to the .gov website. Share sensitive
information only on official, secure websites.
PubMed ID:
36482486
Public Release Type:
Journal
Publication Year: 2022
DOI:
https://doi.org/10.1186/s40168-022-01373-1
Authors:
Islam Md Zohorul, Tran Melissa, Xu Tao, Tierney Braden T., Patel Chirag, Kostic Aleksandar David
Request IDs:
22417
Studies:
The Environmental Determinants of Diabetes in the Young
The gut microbiome promotes specific immune responses, and in turn, the immune system has a hand in shaping the microbiome. Cancer and autoimmune diseases are two major disease families that result from the contrasting manifestations of immune dysfunction. We hypothesized that the opposing immunological profiles between cancer and autoimmunity yield analogously inverted gut microbiome signatures. To test this, we conducted a systematic review and meta-analysis on gut microbiome signatures and their directionality in cancers and autoimmune conditions.
