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PubMed ID:
31128770
Public Release Type:
Journal
Publication Year: 2019
DOI:
https://doi.org/10.1053/j.ajkd.2019.02.024
Authors:
Steubl Dominik, Buzkova Petra, Garimella Pranav S., Ix Joachim H., Devarajan Prasad, Bennett Michael R., Chaves Paolo H. M., Shlipak Michael G., Bansal Nisha, Sarnak Mark J.
Request IDs:
22605
Studies:
Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR)
Uromodulin is released by tubular epithelial cells into the serum and lower levels are associated with more severe interstitial fibrosis and tubular atrophy (IF/TA). Low serum uromodulin (sUMOD) levels are associated with mortality and cardiovascular disease. However, little is known about the association of sUMOD with long-term kidney outcomes in older adults, a population with a high prevalence of IF/TA.
