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PubMed ID:
33170519
Public Release Type:
Journal
Publication Year: 2021
DOI:
https://doi.org/10.1111/jgs.16910
Authors:
Sharma Shilpa, Katz Ronit, Dubin Ruth, Drew David A., Gutierrez Orlando M., Shlipak Michael G., Sarnak Mark J., Ix Joachim H.
Request IDs:
22605
Studies:
Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR)
Fibroblast growth factor (FGF)-23 is a key regulator of mineral metabolism and has been linked with left ventricular hypertrophy in animal models. Most existing epidemiologic studies evaluated a C-terminal FGF23 assay which measures both the intact (active) hormone and inactive fragments. The relationship of intact FGF23 with cause-specific mortality is unknown.
