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PubMed ID:
32906135
Public Release Type:
Journal
Publication Year: 2020
DOI:
https://doi.org/10.1159/000509978
Authors:
Jotwani Vasantha, Garimella Pranav S., Katz Ronit, Malhotra Rakesh, Bates Jeffrey, Cheung Alfred K., Chonchol Michel, Drawz Paul E., Freedman Barry I., Haley William E., Killeen Anthony A., Punzi Henry, Sarnak Mark J., Segal Mark S., Shlipak Michael G., Ix Joachim H.
Request IDs:
22605
Studies:
Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR)
Kidney tubular atrophy on biopsy is a strong predictor of chronic kidney disease (CKD) progression, but tubular health is poorly quantified by traditional measures including estimated glomerular filtration rate (eGFR) and albuminuria. We hypothesized that urinary biomarkers of impaired tubule function would be associated with faster eGFR declines in persons with CKD.
