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PubMed ID:
33306729
Public Release Type:
Journal
Publication Year: 2020
DOI:
https://doi.org/10.1371/journal.pone.0243872
Authors:
Drew David A., Katz Ronit, Kritchevsky Stephen, Ix Joachim H., Shlipak Michael, Newman Anne B., Hoofnagle Andy, Fried Linda, Gutiérrez Orlando M., Sarnak Mark, Ginsberg Stephen D.
Request IDs:
22605
Studies:
Bicarbonate Administration to Stabilize Estimated Glomerular Filtration Rate (eGFR)
Concentrations of fibroblast growth factor 23 (FGF-23), a hormone that regulates phosphorus and vitamin D metabolism, increase as kidney function declines. Excess fibroblast growth factor 23 may impact brain function through promotion of vascular disease or through direct effects on neuronal tissue.
