PubMed ID:
34642772
Public Release Type:
Journal
Publication Year: 2022
DOI:
https://doi.org/10.1007/s00125-021-05573-6
Authors:
Felton Jamie L., Cuthbertson David, Warnock Megan, Lohano Kuldeep, Meah Farah, Wentworth John M., Sosenko Jay, Evans-Molina Carmella
Request IDs:
22818
Studies:
The Environmental Determinants of Diabetes in the Young
Methods to identify individuals at highest risk for type 1 diabetes are essential for the successful implementation of disease-modifying interventions. Simple metabolic measures are needed to help stratify autoantibody-positive (Aab+) individuals who are at risk of developing type 1 diabetes. HOMA2-B is a validated mathematical tool commonly used to estimate beta cell function in type 2 diabetes using fasting glucose and insulin. The utility of HOMA2-B in association with type 1 diabetes progression has not been tested.