PubMed ID:
33692088
Public Release Type:
Journal
Publication Year: 2021
Affiliation: Division of Nephrology, Seattle Children's Hospital, Seattle, Washington.; Division of Nephrology, Kidney Research Institute, University of Washington, Seattle, Washington.; Division of Nephrology, Seattle Children's Hospital, Seattle, Washington.; Division of Nephrology, Kidney Research Institute, University of Washington, Seattle, Washington.
DOI:
https://doi.org/10.1681/ASN.2020081156
Authors:
Kula Alexander J., Prince David K., Flynn Joseph T., Bansal Nisha
Request IDs:
23063
Studies:
The Chronic Kidney Disease in Children Cohort Study
Although young adults (aged 18–40 years) with CKD are at risk for poor cardiovascular and renal outcomes, with hypertension an important and potentially modifiable risk factor, they are largely absent from observational studies and clinical trials of BP in patients with CKD. To address this knowledge gap, this observational study provides a description of BP and its relation to outcomes specifically in young adults with CKD. It demonstrates that among young adults with CKD, higher BP is associated with cardiovascular events (particularly heart failure) and CKD progression. The study’s findings may provide a foundation for future work to develop best practices for BP management in young adults with CKD and improve outcomes.