PubMed ID:
37131628
Public Release Type:
Journal
Publication Year: 2023
DOI:
https://doi.org/10.1101/2023.04.14.23288590
Authors:
Ackerman A. Lenore, Jackson Nicholas J., Caron Ashley T., Kaufman Melissa R., Routh Jonathan C., Lowder Jerry L.
Request IDs:
23065
Studies:
Symptoms of Lower Urinary Tract Dysfunction Phenotyping Study
Patients presenting with lower urinary tract symptoms (LUTS) are historically classified to several symptom clusters, primarily overactive bladder (OAB) and interstitial cystitis/bladder pain syndrome (IC/BPS). Accurate diagnosis, however, is challenging due to overlapping symptomatic features, and many patients do not readily fit into these categories. To enhance diagnostic accuracy, we previously described an algorithm differentiating OAB from IC/BPS. Herein, we sought to validate the utility of this algorithm for identifying and classifying a real-world population of individuals presenting with OAB and IC/BPS and characterize patient subgroups outside the traditional LUTS diagnostic paradigm.